منابع مشابه
Mining cancer genomes in COSMIC
COSMIC, The Catalogue Of Somatic Mutations In Cancer [http://cancer.sanger.ac.uk], is one of the largest repositories for somatic mutational events in human cancer. Data in COSMIC are curated from multiple sources, including from over 14,310 scientific publications, and are alongside data from the Cancer Genome Project at the Sanger Institute and global international consortia, such as The Canc...
متن کاملCOSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer
COSMIC (http://www.sanger.ac.uk/cosmic) curates comprehensive information on somatic mutations in human cancer. Release v48 (July 2010) describes over 136,000 coding mutations in almost 542,000 tumour samples; of the 18,490 genes documented, 4803 (26%) have one or more mutations. Full scientific literature curations are available on 83 major cancer genes and 49 fusion gene pairs (19 new cancer ...
متن کاملTime Delays in Cosmic Ray Propagation
Cosmic Rays (CR) travel at speeds essentially indistinguishable from the speed of light. However whilst travelling through magnetic fields, both regular and turbulent, they are delayed behind the light since they are usually charged particles and their paths are not linear. Those delays can be so long that they are an impediment to correctly identifying sources which may be variable in time. Fu...
متن کاملMining Cytochrome b561 proteins from plant genomes
Cytochrome b561 (Cyt-b561) proteins are important for plant growth, development, and prevention of damage to plants. Because of their high sequence divergence, thorough mining of Cyt-b561 proteins from plant genomes are not easy. Currently there is only one Cyt-b561 gene found in the maize and none in the soybean genome. However, 22 have been identified in the Arabidopsis thaliana genome. We te...
متن کاملMining bacterial genomes for novel arylesterase activity
One hundred and seventy-one genes encoding potential esterases from 11 bacterial genomes were cloned and overexpressed in Escherichia coli; 74 of the clones produced soluble proteins. All 74 soluble proteins were purified and screened for esterase activity; 36 proteins showed carboxyl esterase activity on short-chain esters, 17 demonstrated arylesterase activity, while 38 proteins did not exhib...
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ژورنال
عنوان ژورنال: BMC Proceedings
سال: 2012
ISSN: 1753-6561
DOI: 10.1186/1753-6561-6-s6-p17